Know what you'll monitor before your next model goes live.

We make clinical AI safer and easier to monitor.So you can catch problems early and act with confidence.

Inputs — data, models, clinical context, risk priorities, evidence, policies and thresholds, and who to monitor — pass through SafeAI Health across language, voice, image and structured data, producing evaluation, monitoring, safety signals, subgroup insights, alerts, migration analysis and governance evidence for doctors, auditors and governance teams.

From guesswork to continuous assurance.

Without SafeAI
Higher risk. Less visibility.

AI gets tested once before deployment.

Quality gets judged by vibe checks.

Generic benchmarks define AI quality.

Safety failures can go unnoticed.

Evaluations aren't tailored to workflows.

Model providers become trusted sources.

Subgroup performance remains largely invisible.

Production changes rarely trigger re-evaluation.

With SafeAI
Continuous insight. Greater impact.

AI gets continuously evaluated in production.

Quality reflects real-world clinical performance.

Hospitals define their own evaluations.

Safety-critical failures get actively monitored.

Models are tested across specific subgroups.

Independent engines verify evaluation evidence.

Drift and degradation trigger investigation.

Every decision creates an audit trail.

Incident wall

AI failures are already clinical failures.

Source: AI Incident Database
TruDi surgical navigation

During a sinus procedure, the AI-assisted navigation system allegedly provided incorrect information about the location of surgical instruments. The patient suffered a carotid-artery injury and stroke; the manufacturer disputed that the system caused the injury.

Hospital sepsis alert · dialysis patient

A sepsis-alert system flagged a dialysis patient and prompted treatment toward aggressive IV-fluid administration. A nurse recognised the risk of fluid overload and prevented the recommendation from causing harm.

Sodium bromide advice

A chatbot reportedly suggested sodium bromide could replace sodium chloride. The patient followed the advice, developed severe bromism and psychosis, and required a prolonged hospitalisation.

Medication advice · transplant patient

A kidney-transplant patient reportedly followed chatbot advice and stopped prescribed transplant medication without medical supervision, and subsequently experienced graft failure.

Health-risk algorithm

An algorithm used to identify patients for additional support systematically underestimated the needs of Black patients, because it used healthcare spending as a proxy for healthcare need.

Sepsis prediction model · Michigan Medicine

A sepsis prediction model generated many inaccurate alerts while missing a substantial proportion of patients who developed sepsis — alert fatigue alongside missed deterioration.

The SafeAI workflow

From data to safer care

A continuous loop of evaluation, monitoring, and learning — across every model, modality, and clinical use case.

Continual learning »»»
Ingest Ingest
Define Define
Evaluate Evaluate
Verify Verify
Approve Approve
Deploy Deploy
Monitor Monitor
Detect Detect
Investigate Investigate
Act Act
Learn Learn
Migrate Migrate
««« Safer healthcare
Evaluate

Your clinical teams decide what matters.

The people closest to care define what safe evaluation looks like.
SafeAI turns that expertise into a repeatable evaluation system.

AI proposes
Monitor candidates, subgroups, failure classes and sampling plans.
Verification checks
Backtesting and recomputation before anything is adopted.
Clinical teams stay in control
Approval sits with the people accountable for care.

Create private, institution-specific evaluation datasets and challenge sets that reflect how your teams actually work.

Data residency
Data never leaves your institutional premises.
Built around your data and workflow
Evolving failure and challenge libraries built from your own evidence
SafeAI Health onboarding — clinical context setup: what the model does in your service, which fields must never be missed, what counts as one case, which note types are in scope, the reference standard, and how often monitors run.
Monitor

Six families of monitors.

First we evaluate and set a baseline. Then our agents continuously monitor it, as per the guidelines you set.

Family 01
Performance & calibration
Family 02
Output quality
Family 03
Safety & uncertainty
Family 04
Robustness
Family 05
Subgroup equity
Family 06
Drift
Continuous monitoring · live walkthrough
Alerts

When something changes, do you know whether it matters?

The alert loop: continuous monitoring, assess the severity, route and notify, investigate, take action, learn and improve.
Team

Clinical safety is a multidisciplinary problem.

Clinicians, AI safety researchers, statisticians, engineers, governance leaders and product builders working on one problem: making clinical AI oversight scalable.

Core team

Lara Grosso

Lara Grosso

Harvard DrPH and SafeAI Founder

DrPH at Harvard in AI & patient safety. 10+ years in global health (World Health Organization, CHAI) across 7 countries.

LinkedIn →
Luke Payyapilli

Luke Payyapilli

Seasoned software engineering leader with a track record of scaling systems and guiding technical direction, particularly in cloud infrastructure. Has led product-driven engineering initiatives at multiple successfully acquired companies, collaborating with stakeholders to deliver meaningful outcomes for these organizations and their end users.

LinkedIn →
Francesca Mussa

Francesca Mussa

Harvard PhD and Statistician

PhD, AIM Harvard–BGB. Statistician building clinically meaningful medical AI, grounded in physiology & patient care.

LinkedIn →
Tirtha Pani

Tirtha Pani

AI Safety Engineer

AI Safety scientist building machine learning systems to improve outcomes for people with chronic disease.

LinkedIn →
Isabelle Schulte

Isabelle Schulte

Harvard MPH, Health Management

Head of Business Development. Leads business development, fundraising, hospital partnerships, and GTM strategy. 8+ years in healthcare operations and transformation.

LinkedIn →
Filippo Bargagna

Filippo Bargagna

AI Safety Scientist | Research Fellow @ UNIPI

Supports the technical development of the SafeAI platform and its alignment to the clinical workflow. Research Fellow on ML and Signal Processing at UNIPI.

LinkedIn →
Sanjana Patnam

Sanjana Patnam

AI Safety Engineer Intern

Researches clinical AI failure patterns and builds evaluation frameworks for SafeAI. Graduate student at Northeastern University in Data Analytics Engineering.

LinkedIn →
Tajvir Chahal

Tajvir Chahal

AI Safety Engineer Intern

Building bias/equity audits for SafeAI's clinical AI platform. Background in data analysis; studying Machine Intelligence at Northeastern, with a B.S. in Computer Science from Rutgers.

LinkedIn →
Jonathan Lee

Jonathan Lee

Business Development and Fundraising Intern

Supporting the development of business operations and fundraising of SafeAI Health. Undergraduate student at Northeastern University majoring in Finance.

Clinical partners

Mayo Clinic

Mayo Clinic

Clinical validation partner

Ranked the #1 hospital in the world by Newsweek for eight consecutive years and a perennial U.S. News & World Report Honor Roll hospital.

Humanitas Research Hospital

Humanitas AI

Applied clinical AI research

The AI Center of Humanitas Research Hospital, a leading Italian academic hospital network spanning 12 hospitals.

Advisors

Brian Anderson, MD

Brian Anderson, MD

CEO & Co-Founder, Coalition for Health AI (CHAI)

A physician and digital health pioneer helping shape national standards for trustworthy, safe and effective AI in healthcare. Previously Chief Digital Health Physician at MITRE and head of Informatics and Network Medicine at athenahealth. Harvard Medical School graduate.

Tom Pollard

Tom Pollard

Research Scientist, MIT · Technical Director, PhysioNet

Technical Director of PhysioNet and a contributor to the landmark MIMIC clinical databases. Instructor in Biostatistics at Harvard T.H. Chan School of Public Health, with a PhD in computational modelling of patient physiology.

Cyrus Massoumi

Cyrus Massoumi

Founder & CEO, Dr. B · Founder & Former CEO, Zocdoc

A healthcare entrepreneur and investor who founded Zocdoc and went on to build Dr. B. Founder and Managing Partner of humbition, and a Senior Advisor to Columbia University's Mailman School of Public Health.

Recognition

Awards and accelerators.

Winner · 2025
Harvard Innovation Fund Competition
Winner cohort · 2025
Harvard HealthLab Accelerators
Semifinalists · 2026
President's Innovation Challenge

See it on your own models and data.

Bring us a model, a dataset, or a production monitoring problem. We'll map the evidence, risk, failure modes, and oversight workflow.